The group of Dr. Daniel Panne at EMBL Grenoble is seeking to recruit a Postdoc with a strong interest in applying structural biology approaches. We focus on multi-protein complexes that are relevant in cancer biology and human disease. Areas of focus include understanding epigenetic gene/chromatin regulation and signaling in the innate immune system.

The primary experimental techniques include expression and purification of large complexes, biochemistry of protein or protein-nucleic acid complexes and high resolution structural analysis including crystallography and cryoEM. The candidate will work on structural and functional aspects of the mechanism and regulation of complexes involving the chromatin regulators CBP/p300, building on the structural data and extensive knowhow available in the laboratory.

The successful applicant should hold a Ph.D. degree in biochemistry or biophysics, with a strong background in one or more of these areas: recombinant protein production and purification, crystallographic and biophysical characterization, electron microscopy or protein design. The laboratory has excellent access to state-of-the-art equipment including the ESRF synchrotron, a Tecnai F20 Polara equipped with K2 direct electron detector and other tools for biophysical analysis.

Please apply online through www.embl.org/jobs; Reference number: GR_00086
Additional information is available from Dr. Daniel Panne (panne@embl.fr).

The European Molecular Biology Laboratory (EMBL) is one of the highest  ranked scientific research organisations in the world.
The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy). EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

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