The Department of Chemistry at Uppsala University is inviting applications for two Researcher positions in Computational Biochemistry for the Kamerlin group. These positions are funded by a range of sources including the Swedish Research Council and the Knut and Alice Wallenberg Foundation. The focus of the work will be on using computational tools to understand and guide the evolution of new enzyme functions, with a particular focus on biocatalytic applications.
Duties and responsibilities:
- This is a full time research position that also includes mentorship of junior researchers. The position will include international travel to conferences and meetings with collaborators, when the circumstances allow.
- From a scientific perspective, this position will involve computational integration of simulation and experimental data using a range of molecular simulation tools, including both standard and enhanced molecular dynamics simulations, empirical valence bond and QM/MM simulations, free energy calculations, as well as structural bioinformatics tools.
- Applicant must hold PhD degree in a STEM discipline with a strong background in computational chemistry and/or computational biology, with experience in one or more of the techniques used in the Kamerlin lab.
- Experience in modeling enzyme reaction mechanisms and/or enzyme function-dynamics relationships, in particular in the context of understanding enzyme evolution or for biocatalytic applications or
- Experience in using enhanced sampling approaches (such as replica exchange or metadynamics) to study biomolecular systems, with particular preference given to studies of the role of conformational dynamics in enzyme engineering or evolution.
- Excellent communication skills in written and spoken English, as well as publications of a high scientific standard
Apply online and the application must include:
- Full publication list
- Copies of diplomas and certificates
- Contact details of two references
- Personal letter including a short description of research interests
|Fellowship Level||Technical position|
|Subject areas||Computational Chemistry, Computational Biology|
|Eligibility||Open to all nationalities|
|Deadline||November 2, 2020|