BioMolStruct (Biomolecular Structures and Interactions): PhD program 1546 views

The doc.funds “Biomolecular Structures and Interactions” (BioMolStruct) offers an excellence PhD program that provides an in-depth, multidisciplinary training in biomedical research in a stimulating international environment. The thesis projects center around biomolecules and biomolecular complexes playing essential roles in cellular signaling and metabolism, with a focus on proteins, protein complexes, and lipid/protein interactions that are linked to ageing, cancer, neurodegenerative, metabolic, and cardiovascular diseases as well as genetic disorders.

Requirements:

• Applicants must hold (or be close to obtaining) an undergraduate degree equivalent to a Master in any discipline of natural or life sciences or medicine which included a written master thesis.
• Students who have not yet finished their Masters’ degree can apply but have to be graduated until September 2021.
• Applicants are expected to be highly proficient in this language. A certificate of English proficiency is not mandatory for application but must be provided by the selected students before admission to the PhD program.
• Students of all nationalities are encouraged to apply. Candidates are selected irrespective of sex, race or nationality.

Available Research projects:

• Karl Gruber: Active site cavity and molecular dynamics analyses of mammalian α/β-hydrolase domain (ABHD) containing proteins
• Walter Keller: Structural and functional investigation of the low-affinity IgE receptor CD23
• Tobias Madl: Deciphering the intricate interaction network in the β-catenin destruction complex
• Tobias Madl: Targeting disordered transcription factors
• Gustav Oberdorfer: Mapping of helical folding space using parametric design and high throughput experimental validation
• Monika Oberer: Interactions of physiologically relevant lipases via dynamic regions
• Georg Pabst: Membrane curvature stress-mediated self-aggregation of proteins
• Tea Pavkov-Keller: Interactions of probiotic bacteria with human dendritic cell receptor DCRuth Prassl: Artificial apo-AI peptidomimetic nanodiscs as membrane scaffolds for integral proteins
• Ruth Prassl: High-resolution structure of apolipoprotein B-100 determined by cryo-EMAndreas Winkler: Red-light modulated protein oligomerization for optogenetic applications
• Klaus Zangger: Using pure shift NMR to study the role of disordered proteins in the formation of stress granules

How to apply:

• Download the Application Form and fill it as complete as possible.
• The application form requires the contact details of two referees.
• Recommendation letters send by applicants themselves or by referees not using the questionnaire are not accepted. In addition, scans in pdf format of the following documents must be provided: For all already completed degrees: Transcript of records, Degree certificate, For ongoing studies: Up-to-date transcript of records, Certificate(s) of English proficiency (e.g. IELTS, TOEFL) if applicable.
• The application form and documents must be send to biomolstruct@medunigraz.at in one single e-mail, which does not exceed 10 MB.