EU Marie-Curie PhD Studentship is available in Directed Protein Evolution for Synthetic Biology and Biocatalysis (Fixed Term) at Cambridge University and at the Biocatalysis Research Center of Johnsson Matthey in the Biochemistry Department under the supervision of Dr. F. Hollfelder. The position is available from 1 March 2017 (or later).
Objective of project:
- directed evolution of enzymes for chiral chemo-enzymatic synthesis of industrially relevant enzymes
- use of the most powerful ultrahigh throughput format available, microfluidic droplets, will make selections from libraries with more than a million members possible
- to man-made randomized protein libraries; metagenomic libraries
- Kinetic and structural analysis will help to delineate the chemical and evolutionary mechanisms that allow the emergence of new and improved activities
- Candidate must hold Ist (or upper IInd) class degree in biochemistry, biotechnology, chemistry or a related, relevant subject.
- Candidate must have specific skills in protein engineering, directed evolution, enzymology, bio-catalysis, organic synthesis and familiarity with molecular biology techniques for example cloning, DNA manipulation, preparation and handling of DNA libraries, are advantages.
Duration and Stipend:
- 3 year
- mobility allowance: €7200
- Fixed-term: initially the funds for this post are available for 36 months.
- Description of research interests (cover letter)
- Curriculum Vitae include exam marks and all relevant practical experience.
- 2 References with names and email-addresses (referee must know applicant’s courses or laboratory research work).
- Applications to be sent by email to: firstname.lastname@example.org
|Organization||University of Cambridge|
|Subject areas||Biotechnology, Biochemistry, Chemistry|
|Eligibility||Open for all nationalities|
|Deadline||10 September 2016|
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