The Scientist – Drug Design Computational Modelling for the Alzheimer’s Disease Drug Discovery Centre (ADDD Centre) within the Purdue University Institute for Drug Discovery will be responsible for computer-aided drug design.
- The Computational Modeller will work closely with members of the other technical research cores to analyze crystal and cryo-EM structures to identify drug gable binding sites and then perform in silicon screening (e.g. structure-based, similarity-based, etc.) to identify potential small molecule modulators.
- Additionally, this position will utilize structure-based design to guide the optimization of hit- and lead-compound series from targets co-crystallized with small molecule binders.
- This position will be supported for the duration of the five-year contract of the ADDD Centre.
- Master’s Degree in Computational Chemistry, Computer Science or related field
- Two (2) years of industry experience
- D. Degree
- Experience in designing blood-brain-barrier penetrating compounds
- Expert in drug design modelling software, preferably Schrodinger suite
- Experience in performing large scale virtual screening
- Experience optimizing compound series via structure-based drug design
- Experience working with medicinal chemistry teams to identify and optimize lead compounds for animal and clinical testing
- Purdue will not sponsor employment authorization for this position
- A background check will be required for employment in this position
- FLSA: Exempt (Not Eligible For Overtime
- Retirement Eligibility: Defined Contribution Waiting Period
- Purdue University is an EOE/AA employer. All individuals, including minorities, women, individuals with disabilities, and veterans are encouraged to apply
How can apply:
- Apply online: https://careers.purdue.edu/job/West-Lafayette-Scientist-Drug-Design-Computational-Modeling-Center-for-Alzheimer's-Disease-Drug-Discovery-IN-47906/598287400/
|Type of position||Post doc|
|Subject areas||Computational Chemistry, Computer Science|