Masters, PhD, Potsdoc, Scientist, Fellowships: Purdue University of United States 4242 views

Overview:

The Scientist – Drug Design Computational Modelling for the Alzheimer’s Disease Drug Discovery Centre (ADDD Centre) within the Purdue University Institute for Drug Discovery will be responsible for computer-aided drug design.

1. The Computational Modeller will work closely with members of the other technical research cores to analyze crystal and cryo-EM structures to identify drug gable binding sites and then perform in silicon screening (e.g. structure-based, similarity-based, etc.) to identify potential small molecule modulators.
2. Additionally, this position will utilize structure-based design to guide the optimization of hit- and lead-compound series from targets co-crystallized with small molecule binders.
3. This position will be supported for the duration of the five-year contract of the ADDD Centre.

 Eligibility Criteria:

1. Master’s Degree in Computational Chemistry, Computer Science or related field
2. Two (2) years of industry experience
3. D. Degree
4. Experience in designing blood-brain-barrier penetrating compounds
5. Expert in drug design modelling software, preferably Schrodinger suite
6. Experience in performing large scale virtual screening
7. Experience optimizing compound series via structure-based drug design
8. Experience working with medicinal chemistry teams to identify and optimize lead compounds for animal and clinical testing
9. Purdue will not sponsor employment authorization for this position
10. A background check will be required for employment in this position
11. FLSA: Exempt (Not Eligible For Overtime
12. Retirement Eligibility: Defined Contribution Waiting Period
13. Purdue University is an EOE/AA employer. All individuals, including minorities, women, individuals with disabilities, and veterans are encouraged to apply

How can apply:

1. Apply online: https://careers.purdue.edu/job/West-Lafayette-Scientist-Drug-Design-Computational-Modeling-Center-for-Alzheimer's-Disease-Drug-Discovery-IN-47906/598287400/