Postdoc in Biological chemistry and Drug discovery 1230 views

About the position:

1. Our mission is to discover novel small-molecule degraders to treat cancer and other human diseases with serious unmet medical needs.
2. We are seeking a highly motivated scientist with research experience in structural biology and biophysics.
3. To join a multi-disciplinary drug discovery team based within Dundee’s School of Life Sciences.
4. Under the auspices of a new Protein Degradation Centre.
5. The team is engaged in an exciting collaboration on proteolysis-targeting chimeras
6. (PROTAC) drug discovery between the laboratories of Professor Alessio Ciulli (http://www.lifesci.dundee.ac.uk/groups/alessio-ciulli) and Boehringer Ingelheim.

Eligibility Criteria:

• Doctoral in structural biology, biophysics, biochemistry, chemical biology or a related discipline.
• Highly experienced in molecular biology (construct design, cloning etc.), protein expression, purification and characterisation
• Strong background in structural biology and biophysics, with an emphasis on structure-based drug design.
• Proven expertise with biophysical techniques and assays to study protein-ligand binding and protein-protein interactions
• Experience with either protein crystallization, X-ray data collection (in-house and at synchrotrons), structure solution and model refinement, or protein NMR spectroscopy, or cryo-EM.
• Strong interpersonal, communication and presentation skills.

How to Apply:

• Informal enquiries may be made to Professor Alessio Ciulli, e-mail: ciulli@dundee.ac.uk