Postdoc Fellowship: Antigen/Antibody Complexes 1524 views

The European Molecular Biology Laboratory (EMBL) is inviting application for Postdoc fellowship in High-resolution structure and function of kidney antigen/antibody complexes. The position is available in Germany lab.

Role and responsibilities:

• Project Outline: Membranous nephropathy is caused by autoimmune responses to a number of cell surface proteins at the kidney filtration barrier.
• In this project, we are aiming to determine the full-length structures of two of these antigens, alone and in complex with specifically binding antibodies.
• The structural data together with a clinical group from the University Medical Center Hamburg-Eppendorf (T. Huber, N. Tomas) to elucidate the disease-causing molecular mechanism will be used.
• The fellowship is supported and integrated into research network “Immune-Mediated Glomerular Diseases – Basic Concepts and Clinical Implications”

Requirements:

• Applicant must hold PhD in a relevant field and proven record of scientific accomplishments
• Previously demonstrated expertise in high-resolution structural biology and biophysical approaches including sample preparation (molecular biology, protein purification) and scientific ambition
• International experience and ingenuousness and interest for interdisciplinary work in collaboration with medical researchers
• Excellent communication skills
• Expertise in biochemistry (in vitro and cell-based assays) and cell biology (including imaging) would be advantageous.

How to apply:

apply online and the Reference Number is HH00185.