Postdoctoral Fellowship in Gene Therapy: UBC 1212 views

The Faculty of Pharmaceutical Sciences at University of British Columbia (UBC) has one full-time postdoctoral position available in the lab of Dr. Sarah Hedtrich. Expected start date is negotiable, although a start date as early as possible is considered favorable.

About the project:

• The research project aims for the establishment of an in-situ gene therapy using CRISPR-Cas as a new treatment option for severe monogenic skin diseases.
• Specific aim is the development of smart delivery strategies for CRISPR/Cas components to (diseased) human epithelia with focus on the skin. Secondly, CRISPR/Cas based gene editing strategies will be developed and optimised to correct autosomal recessive congenital ichthyosis (ARCI) causing mutations in human skin.
• Successful candidates will be expected to take the lead within these projects, to publish manuscripts as a first author, and to present their data at conferences and lab meetings.

Requirements:

• Applicants should have a strong background in gene editing using CRISPR-Cas, cell culture and biomolecular methods.
• Experience with primary cells, organ models and non- viral gene delivery are considered strong assets.
• Applicants should have a PhD in Biomedical Engineering, Pharmacology, Biochemistry, or a related field with relevant experience.

Applications:

Applications to be sent via email to sarah.hedtrich@ubc.ca including:

• CV
• Description of research experience
• Statement of research interests
• Names of three referees