RA / Postdoc position in Genetics or Biotechnology at UCL Institute of Neurology, UK 1912 views

Research Associate at DEPARTMENT OF NEURODEGENERATIVE DISEASE,  UCL INSTITUTE OF NEUROLOGY, London, United Kingdom. 

Project: Novel knock-in mouse models of amyotrophic lateral sclerosis and frontotemporal dementia

Description: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating mid-life neurodegenerative disorders for which no cure is currently available. Very large expansions of an intronic hexanucleotide GGGGCC-repeat in the first intron of the C9orf72 gene is the most common genetic cause of both ALS and FTD.

We have made several advances in understanding the underlying disease mechanisms (Mizielinska et al Science 2014, 345:1192-1194; Mizielinska et al Acta Neuropath 2013, 126(6):845-57; Fratta et al Sci Rep 2012, 2:1016).

Required / Qualifications:

• PhD in an appropriate subject, and relevant experience in genetics and DNA manipulation techniques.
• DNA analysis and manipulation of the C9orf72 region for creating the cells required to make our mouse models, and for cellular analyses.

The post is available immediately, and is funded for three years in the first instance by a grant from the Motor Neuron Disease Association. Starting salary on UCL Grade 7 in the range £33,686 – £36,522 per annum inclusive, superannuable.

You should apply for this post through UCL’s online recruitment – http://www.ucl.ac.uk/hr/jobs

where you can download a job description and person specification using ref: 1534650.

If you have any queries regarding the application process,

Please contact :

Samantha Robinson,

Personnel Officer,

Institute of Neurology

(email: IoN.HRAdmin@ucl.ac.uk);

Informal enquiries welcome to

Dr A Isaacs (a.isaacs@ucl.ac.uk).

Deadline:  6 March 2016