Senior Research Chemist Chemistry (UK)   1140 views

The chemistry team at Vertex in Oxford is growing and we currently have an opening in our Exploratory Chemistry team.

We are looking for a Medicinal Chemist with a successful track record of chemical probe and lead generation within the pharmaceutical industry. Outstanding creative, technical, organisational and communication skills are required for this position and the candidate should have the ability to generate and implement new ideas.

The successful candidate will lead by example both in the laboratory and across our early project portfolio.

KEY RESPONSIBILITIES:

  • Designs and performs sophisticated, technically challenging experiments, efficiently and independently
  • Interprets complicated, multidimensional SAR data and generates new design hypotheses
  • Provides innovative medicinal chemistry solutions to answer key biological questions
  • Interprets HTS data, formulates and articulates chemical strategy, reduces strategy to practice and makes recommendations for series progression
  • Introduce new principles/concepts from other fields to help establish new paradigms in Projects · Productively disseminates ideas across discipline- and project-boundaries

Minimum Qualifications

  • Extensive relevant experience of Lead Discovery within the pharmaceutical industry
  • Track record of successfully initiating projects across target classes
  • Up-to-date knowledge of medicinal chemistry
  • Experience of modern hit finding techniques
  • Appreciation of target identification tools and techniques
  • Excellent written and verbal communication skills

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law.

Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.

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