Targeted Anti-Cancer Therapies (TACT): 11 PhD positions 2904 views

TACT (Targeted Anti-Cancer Therapies) is a European Training Network (ETN) funded by the European Commission under the ‘Horizon 2020 research and innovation programme’ and the ‘Marie Skłodowska-Curie actions’ that aims at developing the next generations of treatments against cancer. With a 3.1 M€ funding, TACT ambitions to train 11 PhD students in the development of state-of-the-art targeted anti-cancer therapeutics

Research projects:

1. Synthetic Chemistry: Use of multicomponent reactions as a site-specific method in bioconjugation. University of Strasbourg – France
2. Synthetic Chemistry: Traceless linkers for specific lysosomal release of native drugs. University of Strasbourg – France
3. Mass Spectrometry: New MS-based approaches for Protein-Drug Conjugates characterization at intact & middle- levels. CNRS – France
4. Synthetic Chemistry: Site-specific antibody conjugation based on enzymatic modification–click chemistry. University of Wageningen – Netherlands
5. 5 & 6 Nanomedicine: Development of novel antibody-nanoparticles conjugates. Queen’s University Belfast – United Kingdom
6. Nanomedicine: Application of protein-drug conjugates for the treatment of cancer. Queen’s University Belfast – United Kingdom
7. Chemical Biology: Development of anticalin-drug conjugates (AcDC) as innovative cancer therapies. Technical University of Munich – Germany
8. Chemical Biology: Development of technologies for the next generation protein-drug conjugates (PDC) with improved stability and selectivity. Almac Discovery – United Kingdom
9. Synthetic Chemistry: Selective targeted delivery of complementary toxic drug combinations to cancer cells through the formation of next-generation antibody dual-drug conjugates. University College London – United Kingdom
10. Chemical Biology: In-vivo drug inactivation of amanitin and protein-amanitin conjugates. Heidelberg Pharma – Germany
11. Synthetic Chemistry: Synthesis of new anti-cancer drugs via bioisostere strategy. SpiroChem AG – Switzerland

Requirements:

• Students in various fields at the interface of chemistry, biology and analytical chemistry are eligible to apply. The projects shall start in October, 1st 2020.
• The candidates will have to possess a strong interest in interdisciplinary research and be willing to take part in various communication activities towards non-scientific public.
• Applicants will have to be fluent in English, possess a high degree of self-organisation and be able to work collaboratively.
• Candidates must not have resided or carried out their main activity (e.g. studies) in the country of their potential future host organisation for more than 12 months in the 3 years immediately prior to their recruitment.

Applications:

Applications must be sent by e-mail directly to the personal investigators concerned before including:

• a one-page CV
• a motivation letter
• transcripts of undergraduate studies
• contacts of two references