The Department of Cell and Molecular Biology at Uppsala University has vacant positions available in Jens Carlsson’s group in the computational biology and bioinformatics programme.
About the research:
- Jens Carlsson’s research focuses on using molecular modeling to study protein-ligand interactions, in particular G protein-coupled receptors (GPCRs).
- The GPCR superfamily is a large group of human membrane proteins that plays key roles in physiological processes and are important drug targets.
- The Carlsson group uses structure-based modeling to understand how receptors evolved their functions and to design ligands, often in close collaboration with experimental groups.
- The project is focused on modeling of GPCRs with the goals to understand receptor function at the molecular level and to identify ligands of drug targets.
- The work will involve molecular dynamics simulations to predict receptor structures and how receptors evolved to recognize their ligand. Structure-based virtual screening of large chemical libraries will also be performed to identify ligands of GPCRs.
- Applicant must hold a PhD degree and should have expertise in at least two of these areas: protein structure prediction, molecular docking, molecular dynamics simulations, structure-based drug design.
- Good English language skills and the ability to work in a team are required.
- Experience in modeling of GPCRs and programming/scripting is preferred, but not required.
Apply online and the application should include the following:
- A short letter with a description of research interests and how the candidate could contribute to the project.
- CV with complete publication list.
- Copy of PhD certificate.
- Contact information for at least two references.
|Fellowship Level||Technical positions|
|Subject areas||Chemistry, Computational Biology, Bioinformatics|
|Eligibility||Open to all nationalities|
|Deadline||3 March 2020|