Postdoc: Pharmacokinetics and Metabolomics Analysis 1362 views

Leading Research Fellow at the, Laboratory of Pharmacokinetics and Metabolomics Analysis, Institute for Translational Medicine and Biotechnology.

Position Requirements

Education: Ph.D. in Pharmaceutical Sciences, Analytical Chemistry, Biochemistry or related fields is required.

Experience:

1. More than 02 years of experience in biotechnology or pharmaceutical industry supporting the development of biosimilars/therapeutic proteins;
2. Expertise in state-of-the-art analytical techniques for biologics product such as HRMS, HPLC/UPLC and CE;
3. Experience in peptide mapping, the analytical characterization of a variety of post-translational modifications (PTMs, including: deamidation, oxidation, N-terminal pyroglutamic acid, C-terminal lysine clipping and glycosylation), determination of the positions of disulfide bridges and/or free thiols (sulfhydryl groups);
4. Broad technical expertise and knowledge of diverse laboratory techniques and proven experience training personnel on laboratory techniques and protocols;
5. Experience in defining and implementing analytical control strategies for biological products;
6. Experience and knowledge of key regulatory and quality expectations.

Communication Skills: Excellent verbal/written communication skills and the ability to lead cross functional and/or multi-geography teams.

Key Roles and responsibilities

1. Development of LC-MS and HPLC methods and protocols for biosimilar characterization;
2. Preparation and running of samples on LC-MS and HPLC for biosimilar characterization;
3. Analysis of data using computer software and statistics for biosimilar characterization;
4. Molecular weight determination of biopharmaceutical product (Intact Mass measurement);
5. Peptide mapping for separation and identification of proteins and post translational analysis;
6. Ascertaining N-terminal sequence and C-terminal sequencing of a biopharmaceutical product;
7. Glycosylation studies;
8. Amino acid sequence variants of biopharmaceuticals due to DNA mutations and mistranslations during recombinant production;
9. Perform literature and patent searches to identify the new technologies and the scientific trends;
10. Contribute to the grant funding submissions and establish and manage the external collaborations;
11. Deliver external presentations and publish abstracts and articles;
12. Establish the required internal and external collaborations to successfully execute the projects;

Benefits: If you meet the qualities and skills, and have a necessary experience, then we offer you a job on the following conditions:

1. Full-time contract for one (01) year with possibility of extension;
2. Accommodation on favorable terms at University’s campus;
3. Flight reimbursement in economy class from the place of your living to the Sechenov University’s location;
4. Reimbursement of Health insurance expenses;
5. A salary can be up to RUB150000 after taxes (approximately 2400$) per month depending on your qualifications and scientific performance indicators;
6. Support of excellent mentors and professional administration.

Application Procedure: Submit your online application including a CV, copies of BSc/MSc and PhD transcripts.

For further information please contact Ms Yusifova Samira, at Yusifova_Samira_Eyvaz@Yahoo.com (no applications).