Postdoctoral Fellow in Bioengineering at EMBL Barcelona 1751 views

EMBL Barcelona is a new research unit focusing on Tissue Biology and Disease Modelling. The aim is to go beyond the molecular and cellular scale, integrating gene circuits with a tissue-level quantitative understanding of tissues and organs, both healthy and diseased.

Role and responsibilities:

• The successful candidate will develop and build 3D-BBB models with tubular shape and predetermined network geometry.
• Aim is to mimic vessel dimensions and flow dynamics of the brain vasculature.
• These models incorporate the different cell types that compose the BBB.
• The successful candidate will study how the cells self-organize to recapitulate barrier function, and how the BBB function responds to different physical and biological stimuli, including malaria parasites.
• Depending on the experience and interests, he/she will perform follow up analyses, including functional assays, advanced imaging, transcriptomics or metabolomics.

Requirements:

• Applicant must hold PhD in Bioengineering, Microfluidics or Physics
• Basic experience with tissue engineering and primary cell culture or iPSC differentiation
• Strong interest in cell biology, vascular biology or infectious diseases
• Experience in microscopy and imaging analysis and in transcriptomics, statistics and systems biology
• Knowledge in vascular and blood-brain barrier biology
• Basic wet lab experience, including molecular biology, cell biology and biochemistry