Postdoctoral Fellow: Nanobody Technologies for Structural Biology 869 views

European Molecular Biology Laboratory (EMBL) invites applications for a Postdoctoral Fellow in Nanobody Technologies for Structural Biology for period of 2 years. Candidate is expected to be highly motivated molecular biologist with protein biochemistry expertise to develop the use of single domain antibodies as a platform technology for structural and functional studies.

Study areas:  Structural biology, X-ray crystallography, cryo-electron microscopy

Role and responsibilities:

• To establish an in vitro/in vivo nanobody selection approach to identify binders against selected membrane proteins, which then will be used as tools for structural (X-ray or Cryo-EM) and functional studies (e.g. Imaging, transport assays).
• The work aims at biological discoveries comprising both methodological and applied aspects.
• Candidates’ expertise will be accessible to all interested research groups and teams from the EMBL Hamburg Unit.

Requirements:

• A PhD degree in Biochemistry, Biophysics or Structural Biology (or a related field)
• Strong experience in molecular biology and protein biochemistry with a demonstrated record of accomplishments
• Ability to plan and pursue a research project independently and in a team
• Willingness to learn new skills as projects require
• Good communication, interpersonal and English language skills
• Experience in following may be advantageous: phage display or ribosome display technologies; structural biology (X-ray, Cryo-EM) of integral membrane proteins or larger protein complexes; experimental expertise in the field of membrane transporters; familiarity with eukaryotic expression systems

How to apply:

Apply online

Reference Number: HH00164