Staff Scientist: Cell Signalling Therapies Section 695 views

Spanish National Cancer Research Centre (CNIO) is inviting applications to recruit a Research Scientist who will integrate into a group of nine scientists to identify and validate new cancer targets in the emerging areas of Tumor Metabolism, Immunotherapy and immunometabolism, Cell signaling and Translational research.

Role and responsibilities:

• Selected candidates will be responsible for the design and execution of experiments toward target identification and validation in one of these research disciplines: Cellular cancer biology focusing in the areas of cell signaling and metabolism; Immuno-oncology cancer biology focusing in the identification of novel immunocheckpoints.

Requirements:

• Applicant must hold PhD degree in a Biomedical Science.
• Applicant must al teast have four years of postdoctoral research experience either in pharmaceutical industry or a top academic laboratory.
• Molecular and Cellular biology: experiments involving cell culture of human and mouse cells, 3D culture, biochemistry and molecular biology particularly cloning, retroviral expression systems and gene silencing using shRNAs and CRISPR technology.
• Advanced experience in animal models in particular tumor animal models both spontaneous tumor formation in genetically modify mouse models, as well as xenograft and allogratf models; in vivo imaging.
• Generation, screening and analysis of cDNA and shRNA libraries.
• Knowledge in tumor metabolism (Seahorse analysis, Metabolomics), tumor immunology and immunotherapy will be highly regarded.
• Applicant must possess fluency in English.
• Ability to travel at least once a year.

Applications:

Application to be sent via e-mail to personal@cnio.es (quoting the Reference: SSCST13 in the subject line of the e-mail).